Tanegashima under the Tanegashima clan
The Tanegashima clan came to rule Tanegashima on behalf of the Nagoe family but soon became autonomous. It usually allied with, sometimes submitted itself to, and sometimes antagonized the Shimazu clan on mainland Kyūshū. The Tanegashima clan was given Yakushima and Kuchinoerabu Island by Shimazu Motohisa in 1415. In 1436, it was given the Seven Islands of Kawanabe District, Satsuma Province (the Tokara Islands) and other two islands by Shimazu Mochihisa, the head of a branch family.
Tanegashima is known in Japanese history for the introduction of European firearms to Japan. Around 1543, a Chinese junk with Portuguese merchants on board was driven to Tanegashima. Tanegashima Tokitaka succeeded in reproducing matchlock rifles obtained from the Portuguese. Within a few decades, firearms, then known as tanegashima, were spread across Sengoku Japan.
Toyotomi Hideyoshi's reunification of Japan finalized the Tanegashima clan's status as a senior vassal of the Shimazu clan. It was relocated to Chiran of mainland Kyūshū in 1595. Although it moved back to Tanegashima in 1599, Yakushima and Kuchinoerabu Island fall under the direct control of the Shimazu clan. These islands all constituted Satsuma Domain during the Edo period.
The Amami Islands were a focal point for dispute between the southward-expanding Satsuma Domain and the northward-expanding Ryukyu Kingdom. In 1453, a group of Koreans were shipwrecked on Gaja Island, where they found the island half under the control of Satsuma and half under the control of Ryukyu. Gaja Island is only 80 miles from Satsuma's capital at Kagoshima City. The Koreans noted that the Ryukyuans used guns "as advanced as in Other records of activity in the Amami Islands show Shō Toku's conquest of Kikai Island in 1466, a failed Satsuma invasion of Amami Ōshima in 1493, and two rebellions on Amami Ōshima during the 16th century. The islands were finally conquered by Satsuma during the 1609 Invasion of Ryukyu. The Tokugawa shogunate granted Satsuma the islands in 1624. During the Edo Period, Ryukyuans referred to Satsuma's ships as "Tokara ships".